5-(三氟甲基)-2-吡啶基肼合成路线 （共 5 条）
反应条件
hydrazine hydrate in ethanol T=20 - 90°C;
参考文献
AGIOS PHARMACEUTICALS, INC.; SALITURO, Francesco, G.; SAUNDERS, Jeffrey, O.
Patent: WO2010/118063 A2, 2010 ;
Location in patent: Page/Page column 113 ;
WO 2010/118063 A2
反应条件
hydrazine hydrate in ethanol T=40°C; 24 h;
参考文献
Haga, Takahiro; Fujikawa, Kan-ichi; Koyanagi, Tohru; Nakajima, Toshio; Hayashi, Kouji
Heterocycles, 1984 , vol. 22, # 1 p. 117 - 124
反应条件
hydrazine hydrate in ethanol Heating;
参考文献
Evans; Wah Wong; Wentrup
Journal of the American Chemical Society, 1996 , vol. 118, # 17 p. 4009 - 4017
反应条件
1: 54.5 percent / antimony trifluoride / 0.17 h / Heating 2: 89.7 percent / hydrazine hydrate / ethanol / 24 h / 40 °C View Scheme
参考文献
Heterocycles, , vol. 22, # 1 p. 117 - 124
反应条件
1: diazotization 2: -255.2 °C / Irradiation View Scheme
参考文献
Evans, Richard A.; Wentrup, Curt
Journal of the Chemical Society, Chemical Communications, 1992 , # 15 p. 1062 - 1064
