1-(4,5-二甲基-1,3-噻唑-2-基)甲胺合成路线 （共 3 条）
反应条件
1: With acetic acid; zinc
T=20°C;
2: With hydrogenchloride; ammonium chloride in water; toluene
pH=2;
3: With sodium hydroxide in water
pH=10;
参考文献
Mutabilis
Patent: EP2141164 A1, 2010 ;
Location in patent: Page/Page column 10-11 ;
反应条件
sodium tris(acetoxy)borohydride in dichloromethane; water; ethyl acetate
T=20°C;
参考文献
Zhang, Xuqing; Hufnagel, Heather Rae; Hou, Cuifen; Johnson, Dana L.; Sui, Zhihua; Fegely, Barry; Breslin, David
Patent: US2010/144695 A1, 2010 ;
Location in patent: Page/Page column 53 ;
US 20100144695 A1
反应条件
hydrogenchloride
3 h; Heating;
参考文献
Pyl,T. et al.
Justus Liebigs Annalen der Chemie, 1964 , vol. 676, p. 141 - 150
