2-(5-氨基-1,2,4-噻二唑-3-基)-2(Z)-甲氧基亚胺基乙酸 S-巯基苯并噻唑酯合成路线 (共 2 条)
反应条件
triethylamine; triphenylphosphine in dichloromethane T=0 - 5°C; 6 h; Product distribution / selectivity;
参考文献
WO2010/89729 A1, ;
Page/Page column 25 ;
反应条件
1: With tributyl-amine in tetrahydrofuran; water T=15 - 30°C; pH=6.8 - 7.2; 5.33333 h; 2: With hydrogenchloride in water T=10 - 15°C; pH=~ 1.4;
参考文献
WO2010/89729 A1, ;
Page/Page column 25-26 ;