2-(苄氧基)-4-碘吡啶合成路线 （共 3 条）
反应条件
potassium hydroxide; 18-crown-6 ether in toluene
3.5 h; Heating;
参考文献
Jonsson, Stefan; Odille, Fabrice G. J.; Norrby, Per-Ola; Waernmark, Kenneth
Organic and Biomolecular Chemistry, 2006 , vol. 4, # 10 p. 1927 - 1948
反应条件
1.1: LDA / tetrahydrofuran / 4 h / -78 °C
1.2: 72 percent / I2 / tetrahydrofuran / 1 h / -78 °C
2.1: LDA / tetrahydrofuran / 4 h / -78 °C
2.2: 98 percent / H2O / tetrahydrofuran / 1 h / -78 °C
3.1: 92 percent / KOH; 18-crown-6 / toluene / 3.5 h / Heating
View Scheme
参考文献
Jonsson, Stefan; Odille, Fabrice G. J.; Norrby, Per-Ola; Waernmark, Kenneth
Organic and Biomolecular Chemistry, 2006 , vol. 4, # 10 p. 1927 - 1948
反应条件
1.1: LDA / tetrahydrofuran / 4 h / -78 °C
1.2: 98 percent / H2O / tetrahydrofuran / 1 h / -78 °C
2.1: 92 percent / KOH; 18-crown-6 / toluene / 3.5 h / Heating
View Scheme
参考文献
Jonsson, Stefan; Odille, Fabrice G. J.; Norrby, Per-Ola; Waernmark, Kenneth
Organic and Biomolecular Chemistry, 2006 , vol. 4, # 10 p. 1927 - 1948
