sodium acetate; pyridinium chlorochromate in dichloromethane 1 h; Ambient temperature;

trichlorophosphate T=60°C; 4 h;

1: 98 percent / diisopropylethylamine / dimethylformamide / 0.5 h 2: 1.) sodium borohydride, 2.) potassium carbonate / 1.) EtOH, 5 min, 2.) reflux, 24 h 3: 99.5 percent / tetrabutylammonium fluoride / tetrahydrofuran / 0.17 h 4: 93 percent / pyridinium chlorochromate, sodium acetate / CH2Cl2 / 1 h / Ambient temperature View Scheme

1: 1.) sodium borohydride, 2.) potassium carbonate / 1.) EtOH, 5 min, 2.) reflux, 24 h 2: 99.5 percent / tetrabutylammonium fluoride / tetrahydrofuran / 0.17 h 3: 93 percent / pyridinium chlorochromate, sodium acetate / CH2Cl2 / 1 h / Ambient temperature View Scheme

1: 1.) sodium borohydride, 2.) potassium carbonate / 1.) EtOH, 5 min, 2.) reflux, 24 h 2: 99.5 percent / tetrabutylammonium fluoride / tetrahydrofuran / 0.17 h 3: 93 percent / pyridinium chlorochromate, sodium acetate / CH2Cl2 / 1 h / Ambient temperature View Scheme

1: 99.5 percent / tetrabutylammonium fluoride / tetrahydrofuran / 0.17 h 2: 93 percent / pyridinium chlorochromate, sodium acetate / CH2Cl2 / 1 h / Ambient temperature View Scheme

1: 36 percent / K2CO3 / dimethylformamide 2: 85 percent / phosphorylchloride / 4 h / 60 °C View Scheme