7-苄基-2-[2-(1H-吲哚-3-基)乙基]-2,7-萘啶-1,3(2H,7H)-二酮合成路线 （共 8 条）
反应条件
nickel in tetrahydrofuran
0.166667 h; Heating;
参考文献
Wanner; Koomen; Pandit
Tetrahedron, 1983 , vol. 39, # 22 p. 3673 - 3681
反应条件
1: 1.) (C2H5)3N / 1.) acetonitrile, room temp 1 h, reflux 5 min, 2.) acetonitrile, reflux, 15 min
2: NaOEt / ethanol / 1.) 10 deg C, 1 h, 2.) room temp, 1 h
3: xylene / 0.5 h / Heating
4: 34 percent / Raney Ni / tetrahydrofuran / 0.17 h / Heating
View Scheme
参考文献
Wanner; Koomen; Pandit
Tetrahedron, 1983 , vol. 39, # 22 p. 3673 - 3681
反应条件
1: 1.) (C2H5)3N / 1.) acetonitrile, room temp 1 h, reflux 5 min, 2.) acetonitrile, reflux, 15 min
2: NaOEt / ethanol / 1.) 10 deg C, 1 h, 2.) room temp, 1 h
3: xylene / 0.5 h / Heating
4: 34 percent / Raney Ni / tetrahydrofuran / 0.17 h / Heating
View Scheme
参考文献
Wanner; Koomen; Pandit
Tetrahedron, 1983 , vol. 39, # 22 p. 3673 - 3681
反应条件
1: 1.) (C2H5)3N / 1.) acetonitrile, room temp 1 h, reflux 5 min, 2.) acetonitrile, reflux, 15 min
2: NaOEt / ethanol / 1.) 10 deg C, 1 h, 2.) room temp, 1 h
3: xylene / 0.5 h / Heating
4: 34 percent / Raney Ni / tetrahydrofuran / 0.17 h / Heating
View Scheme
参考文献
Wanner; Koomen; Pandit
Tetrahedron, 1983 , vol. 39, # 22 p. 3673 - 3681
反应条件
1: xylene / 0.5 h / Heating
2: 34 percent / Raney Ni / tetrahydrofuran / 0.17 h / Heating
View Scheme
参考文献
Wanner; Koomen; Pandit
Tetrahedron, 1983 , vol. 39, # 22 p. 3673 - 3681
反应条件
1: NaOEt / ethanol / 1.) 10 deg C, 1 h, 2.) room temp, 1 h
2: xylene / 0.5 h / Heating
3: 34 percent / Raney Ni / tetrahydrofuran / 0.17 h / Heating
View Scheme
参考文献
Wanner; Koomen; Pandit
Tetrahedron, 1983 , vol. 39, # 22 p. 3673 - 3681
反应条件
hydrogenchloride; hydrogen; palladium on activated charcoal in methanol; ethyl acetate
5 h; Ambient temperature;
参考文献
Wanner; Koomen; Pandit
Tetrahedron, 1983 , vol. 39, # 22 p. 3673 - 3681
反应条件
1: 60 percent / H2, HCl / 10percent Pd-C / ethyl acetate; methanol / 5 h / Ambient temperature
2: 70 percent / 40percent HBr-AcOH / 1 h / 40 °C
View Scheme
参考文献
Wanner; Koomen; Pandit
Tetrahedron, 1983 , vol. 39, # 22 p. 3673 - 3681
