[4-(甲硫基)苯基](3-噻吩基)甲酮合成路线 (共 1 条)
反应条件
1: methyl-phenyl-thioether With titanium tetrachloride in dichloromethane
T=0°C; Inert atmosphere;
2: 3-thiophenecarboxylic acid chloride in dichloromethane
T=0 - 20°C; Inert atmosphere;
参考文献
Harrak, Youssef; Casula, Giovanni; Basset, Joan; Rosell, Gloria; Plescia, Salvatore; Raffa, Demetrio; Cusimano, Maria Grazia; Pouplana, Ramon; Pujol, Maria Dolors
Journal of Medicinal Chemistry, 2010 , vol. 53, # 18 p. 6560 - 6571