1-(2-溴-4-甲氧基苯基)-乙酮合成路线 （共 16 条）
反应条件
[{CH3CpZr(OH2)3}2(μ2-OH)2][OSO2C8F17]4 in neat (no solvent)
T=50°C; Friedel-Crafts Acylation; Sealed tubeInert atmosphere;
参考文献
Zhang, Xiaohong; Lou, Cong; Li, Ningbo; Xu, Xinhua; Qiu, Renhua; Yin, Shuangfeng
Journal of Organometallic Chemistry, 2014 , vol. 749, p. 241 - 245
反应条件
1: 3-methoxybromobenzene With triethylsilane; AlCl3, aluminium chloride in dichloromethane
T=0°C; Friedel-Craft's Reaction; 1.16667 h; Inert atmosphere;
2: acetyl chloride in dichloromethane
2 h;
参考文献
GENFIT
Patent: US2010/4159 A1, 2010 ;
Location in patent: Page/Page column 59-60 ;
反应条件
bromine in chloroform
T=0 - 5°C; 1 h;
参考文献
Zara-Kaczian, Erzsebet; Deak, Gyula; Gyoergy, Lajos
Acta Chimica Hungarica, 1989 , vol. 126, # 4 p. 441 - 454
反应条件
aluminium trichloride in carbon disulfide
12 h; Ambient temperature;
参考文献
Takano, Daisuke; Fukunaga, Yuki; Doe, Matsumi; Yoshihara, Kazuo; Kinoshita, Takamasa
Journal of Heterocyclic Chemistry, 1997 , vol. 34, # 4 p. 1111 - 1114
反应条件
lithium perchlorate
T=100°C; 5 h;
参考文献
Bartoli, Giuseppe; Bosco, Marcella; Marcantoni, Enrico; Massaccesi, Massimo; Rinaldi, Samuele; Sambri, Letizia
Tetrahedron Letters, 2002 , vol. 43, # 36 p. 6331 - 6333
反应条件
1: amalgamated zinc; concentrated aqueous HCl
2: glacial acetic acid; aqueous HBr
View Scheme
参考文献
Baddeley; Plant
Journal of the Chemical Society, 1943 , p. 525
