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乙二醇
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63148-62-9
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二甲基亚砜
碳酸氢钠
471-34-1
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乙二醇
甲醛
63148-62-9
MDI
丁酮
二甲基亚砜
碳酸氢钠
471-34-1
897016-92-1
合成路线
(共 4 条)
897016-91-0
→
反应条件
897016-92-1
反应条件
1: With sodium hydroxide; water in tetrahydrofuran T=35°C; 2: With hydrogenchloride; water
参考文献
Hangauer, David G.
Patent: US2006/160800 A1, 2006 ;
Location in patent: Page/Page column 82-83 ;
US 20060160800 A1
1261628-25-4
→
反应条件
897016-92-1
反应条件
1: With methanol; potassium hydroxide T=0 - 20°C; 2: With hydrogenchloride; water
参考文献
Deng, Lisheng; Diao, Jiasheng; Chen, Pinhong; Pujari, Venugopal; Yao, Yuan; Cheng, Gang; Crick, Dean C.; Prasad, B. V. Venkataram; Song, Yongcheng
Journal of Medicinal Chemistry, 2011 , vol. 54, # 13 p. 4721 - 4734
917023-06-4
→
反应条件
897016-92-1
反应条件
1: tetrakis(triphenylphosphine) palladium(0); sodium carbonate / water; toluene / 90 °C / Inert atmosphere 2: methanol; potassium hydroxide / 0 - 20 °C View Scheme
参考文献
Deng, Lisheng; Diao, Jiasheng; Chen, Pinhong; Pujari, Venugopal; Yao, Yuan; Cheng, Gang; Crick, Dean C.; Prasad, B. V. Venkataram; Song, Yongcheng
Journal of Medicinal Chemistry, 2011 , vol. 54, # 13 p. 4721 - 4734
98-80-6
苯硼酸
→
反应条件
897016-92-1
反应条件
1: tetrakis(triphenylphosphine) palladium(0); sodium carbonate / water; toluene / 90 °C / Inert atmosphere 2: methanol; potassium hydroxide / 0 - 20 °C View Scheme
参考文献
Deng, Lisheng; Diao, Jiasheng; Chen, Pinhong; Pujari, Venugopal; Yao, Yuan; Cheng, Gang; Crick, Dean C.; Prasad, B. V. Venkataram; Song, Yongcheng
Journal of Medicinal Chemistry, 2011 , vol. 54, # 13 p. 4721 - 4734