2-(4-氟苯基)-4(5h)-噁唑酮合成路线 （共 3 条）
反应条件
in hexane; dichloromethane
T=0 - 20°C;
参考文献
NOVARTIS AG
Patent: WO2009/115572 A2, 2009 ;
Location in patent: Page/Page column 108 ;
WO 2009/115572 A2
反应条件
sodium hydride in 1,4-dioxane
T=0 - 20°C;
参考文献
Flegeau, Emmanuel Ferrer; Popkin, Matthew E.; Greaney, Michael F.
Organic Letters, 2006 , vol. 8, # 12 p. 2495 - 2498
反应条件
1: 77 percent / toluene / 2 h / 110 °C
2: 34 percent / sodium hydride / dioxane; various solvent(s) / 0 - 20 °C
View Scheme
参考文献
Flegeau, Emmanuel Ferrer; Popkin, Matthew E.; Greaney, Michael F.
Organic Letters, 2006 , vol. 8, # 12 p. 2495 - 2498
