sodium hydroxide in methanol 24 h; Heating;

Stage #1: <b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '8128150', constants.ctx, '0')">sodium hydroxide</a> <br /> <br />Stage #2: <b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '3564799', constants.ctx, '0')">ammonium acetate</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '506007', constants.ctx, '0')">acetic acid</a> <br />5&nbsp;h;&nbsp;&nbsp;Reflux;&nbsp;<br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: NaOH / various solvent(s) / 2 h / 0 &deg;C<br />2: aq. NH₃ / various solvent(s) / 2 h / 100 &deg;C<br /> <br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: NaOH / various solvent(s) / 2 h / 0 &deg;C<br />2: aq. NH₃ / various solvent(s) / 2 h / 100 &deg;C<br /> <br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: 34 percent / piperidine; acetic acid / methanol / 5 h / Heating<br />2: 64 percent / ammonium acetate / methanol / 4 h / Heating<br /> <br /> &nbsp;