N-Boc-4-羟基-L-脯氨酸甲酯合成路线 （共 2 条）
反应条件
sodium chloride; triethylamine in tetrahydrofuran
参考文献
Sankyo Company, Limited
Patent: US5104867 A1, 1992 ;
反应条件
1: 1H-imidazole / N,N-dimethyl-formamide / 1 h / 20 °C 2: lithium borohydride / tetrahydrofuran / 0 - 20 °C 3: triethylamine / dichloromethane / -10 - 20 °C 4: lithium triethylborohydride / tetrahydrofuran / 2 h / 20 °C 5: tetrabutyl ammonium fluoride / tetrahydrofuran / 3 h / 20 °C 6: sodium hydrogencarbonate; Dess-Martin periodane / dichloromethane / 20 °C View Scheme
参考文献
NOVARTIS AG; DILLON, Michael, Patrick; LINDVALL, Mika; POON, Daniel; RAMURTHY, Savithri; RAUNIYAR, Vivek; SHAFER, Cynthia; SUBRAMANIAN, Sharadha; TANNER, Huw
Patent: WO2014/47020 A1, 2014 ;
