sodium hydroxide in methanol Ambient temperature;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '3570522', constants.ctx, '0')">tetrabutyl ammonium fluoride</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '102391', constants.ctx, '0')">tetrahydrofuran</a> <br />22&nbsp;h;&nbsp;&nbsp;Ambient temperature;&nbsp;<br /> &nbsp;

<b>Multi-step reaction with 3 steps<br /> </b>1: 23 percent / K₂CO₃, FClO₃ <br />2: 74 percent / 2,6-lutidine, magnesium triflate, tert-butyltoluene / 0.17 h / Heating<br />3: 98 percent / 1 M Bu₄NF / tetrahydrofuran / 22 h / Ambient temperature<br /> <br /> &nbsp;

<b>Multi-step reaction with 4 steps<br /> </b>1: 2-picoline, magnesium triflate / toluene / 1 h / Heating<br />2: 23 percent / K₂CO₃, FClO₃ <br />3: 74 percent / 2,6-lutidine, magnesium triflate, tert-butyltoluene / 0.17 h / Heating<br />4: 98 percent / 1 M Bu₄NF / tetrahydrofuran / 22 h / Ambient temperature<br /> <br /> &nbsp;

<b>Multi-step reaction with 4 steps<br /> </b>1: 2-picoline, magnesium triflate / benzene / 18 h / Heating<br />2: 13 percent / K₂CO₃, FClO₃ / 15 - 20 &deg;C<br />3: 80 percent / 2-picoline, magnesium triflate / xylene / 2 h / Heating<br />4: 88 percent / 1 M Bu₄NF / tetrahydrofuran / 0.25 h / Ambient temperature<br /> <br /> &nbsp;

<b>Multi-step reaction with 3 steps<br /> </b>1: 13 percent / K₂CO₃, FClO₃ / 15 - 20 &deg;C<br />2: 80 percent / 2-picoline, magnesium triflate / xylene / 2 h / Heating<br />3: 88 percent / 1 M Bu₄NF / tetrahydrofuran / 0.25 h / Ambient temperature<br /> <br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: 89 percent / 2-picoline, magnesium triflate / xylene / 1.5 h / Heating<br />2: 98 percent / 1 M Bu₄NF / tetrahydrofuran / 22 h / Ambient temperature<br /> <br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: 74 percent / 2,6-lutidine, magnesium triflate, tert-butyltoluene / 0.17 h / Heating<br />2: 98 percent / 1 M Bu₄NF / tetrahydrofuran / 22 h / Ambient temperature<br /> <br /> &nbsp;

<b>Multi-step reaction with 4 steps<br /> </b>2: 13 percent / K₂CO₃, FClO₃ / 15 - 20 &deg;C<br />3: 80 percent / 2-picoline, magnesium triflate / xylene / 2 h / Heating<br />4: 88 percent / 1 M Bu₄NF / tetrahydrofuran / 0.25 h / Ambient temperature<br /> <br /> &nbsp;