sodium hydroxide in ethanol

hydrogenchloride in water

sodium hydroxide in ethanol 3 h; Heating; Yield given;

1: dimethylsulfoxide / 1.5 h 2: 2N NaOH / ethanol / 3 h / Heating View Scheme

1: SOCl2 / 0.5 h / Ambient temperature 2: dimethylsulfoxide / 1.5 h 3: 2N NaOH / ethanol / 3 h / Heating View Scheme

1: SOCl2 / 1 h / Heating 2: NaBH4, 2N HCl / 1,2-dimethoxy-ethane / ice cooling 30 min, reflux 30 min 3: SOCl2 / 0.5 h / Ambient temperature 4: dimethylsulfoxide / 1.5 h 5: 2N NaOH / ethanol / 3 h / Heating View Scheme

1: 80.8 percent / 2N NaOH / ethanol / 0.25 h / 90 deg C bath 2: SOCl2 / 1 h / Heating 3: NaBH4, 2N HCl / 1,2-dimethoxy-ethane / ice cooling 30 min, reflux 30 min 4: SOCl2 / 0.5 h / Ambient temperature 5: dimethylsulfoxide / 1.5 h 6: 2N NaOH / ethanol / 3 h / Heating View Scheme

1: triethylamine / CHCl3 2: POCl3 / 0.5 h / 100 - 110 °C 3: 80.8 percent / 2N NaOH / ethanol / 0.25 h / 90 deg C bath 4: SOCl2 / 1 h / Heating 5: NaBH4, 2N HCl / 1,2-dimethoxy-ethane / ice cooling 30 min, reflux 30 min 6: SOCl2 / 0.5 h / Ambient temperature 7: dimethylsulfoxide / 1.5 h 8: 2N NaOH / ethanol / 3 h / Heating View Scheme