3,4-二甲基-1H-吡咯-2-羧酸合成路线 （共 9 条）
反应条件
hydrogen; triethylamine; palladium on activated charcoal in tetrahydrofuran T=25°C; 24 h;
参考文献
Sessler, Jonathan L.; Zimmerman, Rebecca S.; Kirkovits, Gregory J.; Gebauer, Andreas; Scherer, Markus
Journal of Organometallic Chemistry, 2001 , vol. 637-639, p. 343 - 348
反应条件
sodium hydroxide in ethanol; water 16 h; Heating;
参考文献
Roth, Steven D.; Shkindel, Tetyana; Lightner, David A.
Tetrahedron, 2007 , vol. 63, # 45 p. 11030 - 11039
反应条件
hydrogen; palladium on activated charcoal in tetrahydrofuran 19 h;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 1569 - 1576
反应条件
1: SO2Cl2; diethyl ether / Erwaermen des Reaktionsprodukts mit H2O 2: 220 °C 3: methanol. NaOH View Scheme
参考文献
Justus Liebigs Annalen der Chemie, , vol. 554, p. 144,159
反应条件
1: 220 °C 2: methanol. NaOH View Scheme
参考文献
Justus Liebigs Annalen der Chemie, , vol. 554, p. 144,159
反应条件
1: Raney nickel; ethanol / 160 °C / 110326 Torr / Hydrogenation 2: SO2Cl2; diethyl ether / Erwaermen des Reaktionsprodukts mit H2O 3: 250 °C 4: aq.-ethanolic NaOH View Scheme
参考文献
Justus Liebigs Annalen der Chemie, , vol. 533, p. 216,229
反应条件
1: 90 percent / 180 - 190 °C 2: 73 percent / POCl3 / 20 °C View Scheme
参考文献
Dey, Sanjeev K.; Lightner, David A.
Monatshefte fur Chemie, 2008 , vol. 139, # 11 p. 1377 - 1385
参考文献
Chen, Qingqi; Wang, Tianyu; Zhang, Yi; Wang, Qiuan; Ma, Jinshi
Synthetic Communications, 2002 , vol. 32, # 7 p. 1031 - 1040
反应条件
1: 65 percent / H2O / Heating
2: 95 percent / H2O2; pyridine / methanol / Heating
View Scheme
参考文献
Xie, Meiqiang; Lightner, David A.
Tetrahedron, 1993 , vol. 49, # 11 p. 2185 - 2200
