1-(吗啉-4-基磺酰基)哌啶-4-羧酸合成路线 （共 2 条）
反应条件
sodium hydroxide in methanol
T=20 - 85°C; 12 h;
参考文献
Ackermann, Jean; Conte, Aurelia; Neidhart, Werner; Nettekoven, Matthias; Wertheimer, Stanley
Patent: US2011/65707 A1, 2011 ;
Location in patent: Page/Page column 27 ;
反应条件
1: 4-(N,N-dimethlyamino)pyridine / dichloromethane / 12 h / 20 °C / Inert atmosphere
2: sodium hydroxide; water / methanol / 12 h / 85 °C
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参考文献
F. HOFFMANN-LA ROCHE AG; ACKERMANN, Jean; CONTE, Aurelia; NEIDHART, Werner; NETTEKOVEN, Matthias; WERTHEIMER, Stanley
Patent: WO2011/29808 A1, 2011 ;
WO 2011/029808 A1
