7-(1H-咪唑-1-基)-5,6-二氢-2-萘甲酸合成路线 （共 12 条）
反应条件
sulfuric acid in acetic acid
T=100°C; 4 h;
参考文献
Cozzi, P; Branzoli, U; Carganico, G; Ferti, C; Pillan, A; et al.
European Journal of Medicinal Chemistry, 1991 , vol. 26, # 4 p. 423 - 433
反应条件
sodium hydroxide in acetic acid
参考文献
Farmitalia Carlo Erba S.p.A.
Patent: US4510149 A1, 1985 ;
反应条件
1: AlCl3
2: NaOCl, OH-
3: AlCl3, NaCl / Heating
4: Br2 / CHCl3
5: dimethylformamide
6: NaBH4 / methanol
7: H+ / Heating
View Scheme
参考文献
Carganico; Cozzi
Farmaco, 1991 , vol. 46, # SUPPL. 1 p. 209 - 231
反应条件
1: AlCl3, NaCl / Heating
2: Br2 / CHCl3
3: dimethylformamide
4: NaBH4 / methanol
5: H+ / Heating
View Scheme
参考文献
Carganico; Cozzi
Farmaco, 1991 , vol. 46, # SUPPL. 1 p. 209 - 231
反应条件
1: NaOCl, OH-
2: AlCl3, NaCl / Heating
3: Br2 / CHCl3
4: dimethylformamide
5: NaBH4 / methanol
6: H+ / Heating
View Scheme
参考文献
Carganico; Cozzi
Farmaco, 1991 , vol. 46, # SUPPL. 1 p. 209 - 231
反应条件
1: Br2 / CHCl3
2: dimethylformamide
3: NaBH4 / methanol
4: H+ / Heating
View Scheme
参考文献
Carganico; Cozzi
Farmaco, 1991 , vol. 46, # SUPPL. 1 p. 209 - 231
反应条件
1: dimethylformamide
2: NaBH4 / methanol
3: H+ / Heating
View Scheme
参考文献
Carganico; Cozzi
Farmaco, 1991 , vol. 46, # SUPPL. 1 p. 209 - 231
反应条件
1: NaBH4 / methanol
2: H+ / Heating
View Scheme
参考文献
Carganico; Cozzi
Farmaco, 1991 , vol. 46, # SUPPL. 1 p. 209 - 231
反应条件
thionyl chloride in ethanol
参考文献
Farmitalia Carlo Erba S.p.A.
Patent: US4510149 A1, 1985 ;
反应条件
thionyl chloride
24 h; Heating;
参考文献
Cozzi, P; Branzoli, U; Carganico, G; Ferti, C; Pillan, A; et al.
European Journal of Medicinal Chemistry, 1991 , vol. 26, # 4 p. 423 - 433
