potassium hydroxide in ethylene glycol T=140°C; 2 h;

1: 1.) 20 M NaOH / 1.) DMF, r.t., 2 h, 2.) r.t., 2 h 2: 40 percent / aq. KOH / ethane-1,2-diol / 2 h / 140 °C View Scheme