2-氨基-7-硝基苯并噻唑合成路线 （共 6 条）
反应条件
bromine in chloroform 3 h; Reflux;
参考文献
YUHAN CORPORATION; HUR, Youn; KIM, Dong-Hyun; KIM, Eun-Kyung; PARK, Jin-Hwi; JOO, Jae-Eun; KANG, Ho-Woong; OH, Se-Woong; KIM, Dong-Kyun; AHN, Kyoung-Kyu
Patent: WO2013/43001 A1, 2013 ;
Location in patent: Paragraph 243; 244; 245 ;
反应条件
1: sodium methylate; methanol / 20 °C 2: bromine / chloroform / 3 h / |Reflux View Scheme
反应条件
1: chlorobenzene 2: bromine; chlorobenzene View Scheme
参考文献
Ukrainskii Khimicheskii Zhurnal (Russian Edition), , vol. 22, p. 363,365
Chem.Abstr., , p. 4358
反应条件
tert.-butylnitrite; copper dichloride in DMF (N,N-dimethyl-formamide) T=20°C; 24 h;
参考文献
TAKEDA PHARMACEUTICAL COMPANY LIMITED
Patent: WO2005/44793 A2, 2005 ;
Location in patent: Page/Page column 104 ;
WO 2005/044793 A2
反应条件
1: With hydrogen bromide; bromine; sodium nitrite in water; acetic acid T=0 - 5°C; 2 h; 2: With sodium hydroxide in water
参考文献
TAKEDA PHARMACEUTICAL COMPANY LIMITED
Patent: WO2005/44793 A2, 2005 ;
Location in patent: Page/Page column 111 ;
WO 2005/044793 A2
反应条件
hydrogenchloride; tin(ll) chloride
参考文献
Wel'tman
Ukrainskii Khimicheskii Zhurnal (Russian Edition), 1956 , vol. 22, p. 363,365
Chem.Abstr., 1957 , p. 4358
