6-溴-2-吡啶甲醛1-氧化物合成路线 （共 4 条）
反应条件
manganese(IV) oxide in 1,4-dioxane
T=90°C; 1 h;
参考文献
Landa, Aitor; Minkkilae, Anna; Blay, Gonzalo; Jergensen, Karl Anker
Chemistry - A European Journal, 2006 , vol. 12, # 13 p. 3472 - 3483
反应条件
1.1: n-BuLi / diethyl ether; hexane / 0.08 h / -78 °C
1.2: diethyl ether; hexane / -78 - -10 °C
2.1: 5.2 g / NaBH4 / methanol / 1 h / 20 °C
3.1: 85 percent / m-CPBA / CHCl3 / 20 h / 65 - 70 °C
4.1: 61 percent / MnO2 / dioxane / 1 h / 90 °C
View Scheme
参考文献
Landa, Aitor; Minkkilae, Anna; Blay, Gonzalo; Jergensen, Karl Anker
Chemistry - A European Journal, 2006 , vol. 12, # 13 p. 3472 - 3483
反应条件
1: 5.2 g / NaBH4 / methanol / 1 h / 20 °C
2: 85 percent / m-CPBA / CHCl3 / 20 h / 65 - 70 °C
3: 61 percent / MnO2 / dioxane / 1 h / 90 °C
View Scheme
参考文献
Landa, Aitor; Minkkilae, Anna; Blay, Gonzalo; Jergensen, Karl Anker
Chemistry - A European Journal, 2006 , vol. 12, # 13 p. 3472 - 3483
反应条件
1: 85 percent / m-CPBA / CHCl3 / 20 h / 65 - 70 °C
2: 61 percent / MnO2 / dioxane / 1 h / 90 °C
View Scheme
参考文献
Landa, Aitor; Minkkilae, Anna; Blay, Gonzalo; Jergensen, Karl Anker
Chemistry - A European Journal, 2006 , vol. 12, # 13 p. 3472 - 3483
