Cr3(OAc)7(OH)2; periodic acid in acetonitrile T=20°C; 24 h;

5 Pd(II)/C(eggshell); hydrogen in methanol 3 h;

in dichloromethane 1 h;

1: 4-iodobenzoic acid ethyl ester; potassium triisopropylsilane-thiolate With tetrakis(triphenylphosphine) palladium(0) in toluene T=90°C; 1 h; 2: With sulfuryl dichloride; potassium nitrate in acetonitrile T=0°C; 3: diethylamine in acetonitrile

in tetrahydrofuran T=20 - 22°C; 14 h;

1: 92 percent / 4-(N,N-dimethylamino)pyridine / tetrahydrofuran / 0.17 h / 20 °C 2: 28 percent / tetrahydrofuran / 14 h / 20 - 22 °C View Scheme