(3-氯苄基)-吡啶-2-胺双盐酸盐合成路线 （共 3 条）
反应条件
1.1: tert-butyl alcohol / 24 h / 25 °C
2.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0 - 5 °C
2.2: 1.5 h / 5 - 20 °C
3.1: trifluoroacetic acid / water; dichloromethane
View Scheme
参考文献
Liang, Dongdong; He, Yimiao; Liu, Lanying; Zhu, Qiang
Organic Letters, 2013 , vol. 15, # 13 p. 3476 - 3479
反应条件
1.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0 - 5 °C
1.2: 1.5 h / 5 - 20 °C
2.1: trifluoroacetic acid / water; dichloromethane
View Scheme
参考文献
Liang, Dongdong; He, Yimiao; Liu, Lanying; Zhu, Qiang
Organic Letters, 2013 , vol. 15, # 13 p. 3476 - 3479
反应条件
trifluoroacetic acid in dichloromethane; water
参考文献
Liang, Dongdong; He, Yimiao; Liu, Lanying; Zhu, Qiang
Organic Letters, 2013 , vol. 15, # 13 p. 3476 - 3479
