4-氨基-6-甲基-2-(甲基硫代)-5-嘧啶甲腈合成路线 （共 2 条）
反应条件
1: With sodium methylate in methanol
T=0 - 20°C;
2: With water in methanol
0.5 h;
参考文献
SMITHKLINE BEECHAM CORPORATION; ATKINSON, Francis, Louis; AXTEN, Jeffrey, Michael; CICHY-KNIGHT, Maria; MOORE, Michael, Lee; PATEI, Vipulkumar, Kantibhai; TIAN, Xinrong; WELLAWAY, Christopher, Roland; DUNN, Allison, K.
Patent: WO2010/19637 A1, 2010 ;
Location in patent: Page/Page column 54 ;
WO 2010/019637 A1
反应条件
sodium methylate in methanol; water
参考文献
ABBVIE INC.; Vasudevan, Anil; Penning, Thomas Dale; Chen, Huanming; Liang, Bo; Wang, Shaohui; Zhao, Zhongqiang; Chai, Dikun; Yang, Leifu; Gao, Yingxiang; Pliushchev, Marina
Patent: US2014/171429 A1, 2014 ;
Location in patent: Page/Page column ;
