1: n-BuLi / hexamethylphosphoric acid triamide; tetrahydrofuran; hexane / -78 - 20 °C
2: 95 percent / imidazole / dimethylformamide / 12 h / Ambient temperature
View Scheme
参考文献
Bures, Edward; Spinazze, Patrick G.; Beese, Giovanna; Hunt, Ian R.; Rogers, Christine; Keay, Brian A.
Journal of Organic Chemistry, 1997 , vol. 62, # 25 p. 8741 - 8749
1: 96 percent / NaH / dimethylformamide / 1 h / Ambient temperature
2: 95 percent / imidazole / dimethylformamide / 12 h / Ambient temperature
View Scheme
参考文献
Bures, Edward; Spinazze, Patrick G.; Beese, Giovanna; Hunt, Ian R.; Rogers, Christine; Keay, Brian A.
Journal of Organic Chemistry, 1997 , vol. 62, # 25 p. 8741 - 8749
1: 92 percent / NaH / tetrahydrofuran / 16 h / Ambient temperature
2: 95 percent / imidazole / dimethylformamide / 12 h / Ambient temperature
View Scheme
参考文献
Bures, Edward; Spinazze, Patrick G.; Beese, Giovanna; Hunt, Ian R.; Rogers, Christine; Keay, Brian A.
Journal of Organic Chemistry, 1997 , vol. 62, # 25 p. 8741 - 8749
1: 12 percent / LDA / hexamethylphosphoric acid triamide; tetrahydrofuran / 0.25 h / -78 °C
2: 77 percent / LiAlH4 / diethyl ether / 6 h / Ambient temperature
3: 95 percent / imidazole / dimethylformamide / 12 h / Ambient temperature
View Scheme
参考文献
Bures, Edward; Spinazze, Patrick G.; Beese, Giovanna; Hunt, Ian R.; Rogers, Christine; Keay, Brian A.
Journal of Organic Chemistry, 1997 , vol. 62, # 25 p. 8741 - 8749
1: LDA / hexamethylphosphoric acid triamide; tetrahydrofuran / 0.25 h / -78 °C
2: 77 percent / LiAlH4 / diethyl ether / 6 h / Ambient temperature
3: 95 percent / imidazole / dimethylformamide / 12 h / Ambient temperature
View Scheme
参考文献
Bures, Edward; Spinazze, Patrick G.; Beese, Giovanna; Hunt, Ian R.; Rogers, Christine; Keay, Brian A.
Journal of Organic Chemistry, 1997 , vol. 62, # 25 p. 8741 - 8749
1: LDA / hexamethylphosphoric acid triamide; tetrahydrofuran / 0.25 h / -78 °C
2: 77 percent / LiAlH4 / diethyl ether / 6 h / Ambient temperature
3: 95 percent / imidazole / dimethylformamide / 12 h / Ambient temperature
View Scheme
参考文献
Bures, Edward; Spinazze, Patrick G.; Beese, Giovanna; Hunt, Ian R.; Rogers, Christine; Keay, Brian A.
Journal of Organic Chemistry, 1997 , vol. 62, # 25 p. 8741 - 8749
1: LDA / hexamethylphosphoric acid triamide; tetrahydrofuran / 0.25 h / -78 °C
2: 77 percent / LiAlH4 / diethyl ether / 6 h / Ambient temperature
3: 95 percent / imidazole / dimethylformamide / 12 h / Ambient temperature
View Scheme
参考文献
Bures, Edward; Spinazze, Patrick G.; Beese, Giovanna; Hunt, Ian R.; Rogers, Christine; Keay, Brian A.
Journal of Organic Chemistry, 1997 , vol. 62, # 25 p. 8741 - 8749