peracetic acid; sodium acetate in dichloromethane T=7°C; 3.5 h;

1: 90 percent / BuLi / tetrahydrofuran / 12 h / 0 °C 2: 90 percent / BuLi / tetrahydrofuran / 12 h / 0 °C 3: 95 percent / HCl / methanol / 1 h / Ambient temperature 4: 80 percent / Raney nickel / ethanol / 16 h / Heating 5: 95 percent / imidazole / dimethylformamide / 12 h / Ambient temperature 6: 88 percent / HOOAc, NaOAc / CH2Cl2 / 3.5 h / 7 °C View Scheme

1: 95 percent / imidazole / dimethylformamide / 12 h / Ambient temperature 2: 88 percent / HOOAc, NaOAc / CH2Cl2 / 3.5 h / 7 °C View Scheme

1: BuLi 2: 88 percent / HOOAc, NaOAc / CH2Cl2 / 3.5 h / 7 °C View Scheme

1: 90 percent / BuLi / tetrahydrofuran / 12 h / 0 °C 2: 95 percent / HCl / methanol / 1 h / Ambient temperature 3: 80 percent / Raney nickel / ethanol / 16 h / Heating 4: 95 percent / imidazole / dimethylformamide / 12 h / Ambient temperature 5: 88 percent / HOOAc, NaOAc / CH2Cl2 / 3.5 h / 7 °C View Scheme

1: 80 percent / Raney nickel / ethanol / 16 h / Heating 2: 95 percent / imidazole / dimethylformamide / 12 h / Ambient temperature 3: 88 percent / HOOAc, NaOAc / CH2Cl2 / 3.5 h / 7 °C View Scheme

1: 95 percent / HCl / methanol / 1 h / Ambient temperature 2: 80 percent / Raney nickel / ethanol / 16 h / Heating 3: 95 percent / imidazole / dimethylformamide / 12 h / Ambient temperature 4: 88 percent / HOOAc, NaOAc / CH2Cl2 / 3.5 h / 7 °C View Scheme

1: 95 percent / imidazole / dimethylformamide / 12 h / Ambient temperature 2: 88 percent / HOOAc, NaOAc / CH2Cl2 / 3.5 h / 7 °C View Scheme