4-氨基-6-苯基-3(2H)-哒嗪酮合成路线 （共 5 条）
反应条件
sodium hydroxide; bromine in water
1. 0 degC, 30min., then steam bath, 3h;
参考文献
Sircar
Journal of Heterocyclic Chemistry, 1983 , vol. 20, # 6 p. 1473 - 1476
反应条件
1: T=100°C;
2: With ammonium hydroxide
3: With hydrazine hydrate
Heating;
参考文献
Mitchinson, Andrew; Blackaby, Wesley P.; Bourrain, Sylvie; Carling, Robert W.; Lewis, Richard T.
Tetrahedron Letters, 2006 , vol. 47, # 13 p. 2257 - 2260
反应条件
1: NH3 / ethanol / Heating
2: AcOH / Heating
View Scheme
参考文献
Costantino, Luca; Rastelli, Giulio; Gamberini, M. Cristina; Giovannoni, M. Paola; Piaz, Vittorio Dal; Vianello, Paola; Barlocco, Daniela
Journal of Medicinal Chemistry, 1999 , vol. 42, # 11 p. 1894 - 1900
反应条件
1: 68 percent / NH3 / methanol / Ambient temperature; overnight
2: 80 percent / bromine, NaOH / H2O / 1. 0 degC, 30min., then steam bath, 3h
View Scheme
参考文献
Sircar
Journal of Heterocyclic Chemistry, 1983 , vol. 20, # 6 p. 1473 - 1476
反应条件
acetic acid
Heating;
参考文献
Costantino, Luca; Rastelli, Giulio; Gamberini, M. Cristina; Giovannoni, M. Paola; Piaz, Vittorio Dal; Vianello, Paola; Barlocco, Daniela
Journal of Medicinal Chemistry, 1999 , vol. 42, # 11 p. 1894 - 1900
