反应条件
1: 77 percent / NaOMe / methanol / 25 deg C -> reflux
2: 1.) NaBH4, 2.) diisobutylaluminum hydride / 1.) methanol, -55 deg C; 2.) toluene, -78 deg C
3: pyridine / CH2Cl2 / 25 °C
4: HMPA / 25 °C
5: 1.) aq. NaOH / 1.) reflux
6: H2 / Lindlar catalyst
7: pyridine / CH2Cl2 / 0 °C
8: Et3N / -20 °C
9: 1.) NaOMe, MeOH, 2.) Collins reagent, 3.) DBU
View Scheme
参考文献
Ohuchida, Shuichi; Hamanaka, Nobuyuki; Hayashi, Masaki
Journal of the American Chemical Society, 1981 , vol. 103, # 15 p. 4597 - 4599
