1: acetic anhydride; 2-Amino-5-bromo-3-methyl-benzoic acid methyl ester With potassium acetate in chloroform T=0 - 20°C; 0.25 h; 2: isopentyl nitrite With 18-crown-6 ether in chloroform T=65°C; 18 h;

1: With potassium acetate; isopentyl nitrite in chloroform T=20°C; Heating / reflux; 2: With hydrogenchloride in methanol T=20°C; 4 h;

1.1: N-bromosuccinmide / N,N-dimethyl-formamide / 6 h / 20 °C 2.1: potassium acetate / chloroform / 0.25 h / 0 - 20 °C 2.2: 18 h / 65 °C 3.1: hydrogenchloride / water; methanol / 2 h / 20 °C View Scheme

1.1: potassium acetate / chloroform / 0.25 h / 0 - 20 °C 1.2: 18 h / 65 °C 2.1: hydrogenchloride / water; methanol / 2 h / 20 °C View Scheme