环己基[3-(1,3-二氧戊环-2-基)苯基]甲酮合成路线 (共 1 条)
反应条件
1: 2-(3-bromo-phenyl)-[1,3]-dioxolane With diisobutyl-aluminum chloride in tetrahydrofuran T=-78°C; Inert atmosphereSchlenk technique; 2: With n-butyllithium in tetrahydrofuran; hexane T=-78 - 20°C; Inert atmosphereSchlenk technique; 3: cyclohexane carboxylic acid chloride With CuCN*2LiCl in tetrahydrofuran; hexane T=-40 - 25°C; Inert atmosphere;
参考文献
Klatt, Thomas; Groll, Klaus; Knochel, Paul
Chemical Communications, 2013 , vol. 49, # 62 p. 6953 - 6955