5-(4-氟苯基)-5-氧代戊腈合成路线 （共 4 条）
反应条件
sodium carbonate in water 12 - 15 h; Reflux;
参考文献
Streuff, Jan; Feurer, Markus; Bichovski, Plamen; Frey, Georg; Gellrich, Urs
Angewandte Chemie - International Edition, 2012 , vol. 51, # 34 p. 8661 - 8664
反应条件
1.1: sodium hydride / ethanol / 40 - 50 °C / Inert atmosphere 1.2: 2 h / 20 °C / Inert atmosphere 2.1: sodium carbonate / water / 12 - 15 h / Reflux View Scheme
参考文献
Angewandte Chemie - International Edition, , vol. 51, # 34 p. 8661 - 8664
反应条件
1.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.5 h / 10 - 20 °C / Inert atmosphere 1.2: 10 - 20 °C / Inert atmosphere 2.1: sodium hydride / ethanol / 40 - 50 °C / Inert atmosphere 2.2: 2 h / 20 °C / Inert atmosphere 3.1: sodium carbonate / water / 12 - 15 h / Reflux View Scheme
参考文献
Angewandte Chemie - International Edition, , vol. 51, # 34 p. 8661 - 8664
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 12, # 11 p. 1501 - 1505
