8-(4-甲氧基苯基)-8-氧代辛烷腈合成路线 (共 2 条)
反应条件
1: ω-chloroheptanenitrile With iron (III) acetylacetonate; para-fluorostyrene; (4-Me2NC6H4)2Zn(iPr)MgCl in tetrahydrofuran T=25°C; 16 h; Inert atmosphere; 2: 4-methoxy-benzoyl chloride With CuCN*2LiCl in tetrahydrofuran T=-20°C; 0.5 h; Inert atmosphere;
参考文献
Melzig, Laurin; Diene, Coura R.; Rohbogner, Christoph J.; Knochel, Paul
Organic Letters, 2011 , vol. 13, # 12 p. 3174 - 3177
反应条件
gold(III) chloride; N,N,N',N,-tetramethylethylenediamine; copper diacetate; zinc in water T=20°C; 24 h; Inert atmosphere;
参考文献
Lipshutz, Bruce H.; Huang, Shenlin; Leong, Wendy Wen Yi; Zhong, Guofu; Isley, Nicholas A.
Journal of the American Chemical Society, 2012 , vol. 134, # 49 p. 19985 - 19988