2-氯-5-甲基磺酰基苯甲酸合成路线 （共 5 条）
反应条件
1: With ammonia; copper in water T=125 - 130°C; 18 h; 2: With hydrogenchloride in water pH=2;
参考文献
Jolidon, Synese J.; Narquizian, Robert; Nettekoven, Matthias Heinrich; Norcross, Roger David; Pinard, Emmanuel; Stalder, Henri
Patent: US2005/209241 A1, 2005 ;
Location in patent: Page/Page column 16-17; 20 ;
US 20050209241 A1
反应条件
1: With sodium hydroxide; sodium hydrogencarbonate in water; acetone
T=20°C; 0.0833333 h;
2: With Oxonereg; in water; acetone
1 h;
3: With hydrogenchloride in water; acetone
参考文献
BIOLIPOX AB
Patent: WO2007/42816 A1, 2007 ;
Location in patent: Page/Page column 36 ;
WO 2007/042816 A1
反应条件
1: With sodium hydroxide in methanol; water
T=80°C; pH=9; 48 h;
2: With hydrogenchloride in water
参考文献
Jolidon, Synese; Narquizian, Robert; Norcross, Roger David; Pinard, Emmanuel
Patent: US2006/148797 A1, 2006 ;
Location in patent: Page/Page column 7 ;
反应条件
1: With methanol; sodium hydroxide; water
T=70°C; 18 h;
2: With hydrogenchloride in water
pH=1;
参考文献
GLAXO GROUP LIMITED
Patent: WO2006/94840 A1, 2006 ;
Location in patent: Page/Page column 36-37 ;
参考文献
Cell Pathways, Inc.
Patent: US5942520 A1, 1999 ;
