4-氯-6-乙基-2-甲基嘧啶合成路线 （共 11 条）
反应条件
trichlorophosphate 2 h; Heating;
参考文献
Sakamoto, Takao; Yoshizawa, Hiroshi; Kaneda, Sohichi; Hama, Yoshiaki; Yamanaka, Hiroshi
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 12 p. 4533 - 4538
反应条件
1: 82 percent / Na/MeOH / Ambient temperature 2: 41 percent / POCl3 / 2 h / Heating View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 31, # 12 p. 4533 - 4538
反应条件
1: 79 percent / zinc/satd. aq. NaCl/5percent ammonia / benzene / 12 h / Heating 2: 67 percent / propyl nitrite, HCl / ethanol / 2 h / Ambient temperature 3: 32 percent / selenium dioxide, pyridine / dioxane / 5 h / Heating View Scheme
参考文献
Sakamoto, Takao; Sakasai, Takeji; Yoshizawa, Hiroshi; Tanji, Ken-Ichi; Nishimura, Sumiko; Yamanaka, Hiroshi
Chemical & Pharmaceutical Bulletin, 1983 , vol. 31, # 12 p. 4554 - 4560
反应条件
ammonium hydroxide; sodium chloride; zinc in benzene
12 h; Heating;
参考文献
Sakamoto, Takao; Sakasai, Takeji; Yoshizawa, Hiroshi; Tanji, Ken-Ichi; Nishimura, Sumiko; Yamanaka, Hiroshi
Chemical & Pharmaceutical Bulletin, 1983 , vol. 31, # 12 p. 4554 - 4560
反应条件
1: 84 percent / 1.) Mg; 2.) Ni(dppp)Cl2 / diethyl ether / 6 h / Heating
2: 31 percent / m-chloroperbenzoic acid
3: phosphoryl chloride / dioxane / Heating
View Scheme
参考文献
Sakamoto, Takao; Yoshizawa, Hiroshi; Kaneda, Sohichi; Hama, Yoshiaki; Yamanaka, Hiroshi
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 12 p. 4533 - 4538
反应条件
[1,3-bis(diphenylphosphino) propane] dichloronickel(II); magnesium in diethyl ether
6 h; Heating;
参考文献
Sakamoto, Takao; Yoshizawa, Hiroshi; Kaneda, Sohichi; Hama, Yoshiaki; Yamanaka, Hiroshi
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 12 p. 4533 - 4538
反应条件
sodium
2 h; Heating;
参考文献
Sakamoto, Takao; Yoshizawa, Hiroshi; Kaneda, Sohichi; Hama, Yoshiaki; Yamanaka, Hiroshi
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 12 p. 4533 - 4538
反应条件
1: 84 percent / 1.) Mg; 2.) Ni(dppp)Cl2 / diethyl ether / 6 h / Heating
2: 31 percent / m-chloroperbenzoic acid
View Scheme
参考文献
Sakamoto, Takao; Yoshizawa, Hiroshi; Kaneda, Sohichi; Hama, Yoshiaki; Yamanaka, Hiroshi
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 12 p. 4533 - 4538
反应条件
1: 81 percent / Na / 2 h / Heating
2: 44 percent / m-chloroperbenzoic acid
View Scheme
参考文献
Sakamoto, Takao; Yoshizawa, Hiroshi; Kaneda, Sohichi; Hama, Yoshiaki; Yamanaka, Hiroshi
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 12 p. 4533 - 4538
反应条件
1: 81 percent / Na / 2 h / Heating
2: 44 percent / m-chloroperbenzoic acid
3: 59 percent / phosphoryl chloride / dioxane / Heating
View Scheme
参考文献
Sakamoto, Takao; Yoshizawa, Hiroshi; Kaneda, Sohichi; Hama, Yoshiaki; Yamanaka, Hiroshi
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 12 p. 4533 - 4538
