反应条件
1.1: potassium carbonate / acetone / 6 h / Reflux 2.1: hydrazine / water; diethylene glycol / 120 - 190 °C 2.2: 6 h / 120 - 130 °C 3.1: tin(IV) chloride / carbon disulfide / 5 - 20 °C / Inert atmosphere; Cooling with ice 4.1: ethyl mercaptan sodium salt / N,N-dimethyl-formamide / 1 h / 125 - 130 °C 5.1: N-bromosuccinmide / dichloromethane; N,N-dimethyl-formamide / 17 h / -10 - 20 °C View Scheme
参考文献
Wempe, Michael F.; Jutabha, Promsuk; Quade, Bettina; Iwen, Timothy J.; Frick, Morin M.; Ross, Ian R.; Rice, Peter J.; Anzai, Naohiko; Endou, Hitoshi
Journal of Medicinal Chemistry, 2011 , vol. 54, # 8 p. 2701 - 2713