8-氨基-6-甲氧基喹啉合成路线 （共 86 条）
反应条件
18-crown-6 ether in 1,4-dioxane; tert-butyl alcohol 4 h; Irradiation; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 1911 - 1916
反应条件
pyrrolidine; N,N,N',N,-tetramethylethylenediamine Ambient temperatureIrradiation;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 10 p. 2495 - 2500
反应条件
1: acetic acid; nitric acid / zuletzt bei 60grad 2: arsenic acid; sulfuric acid / 140 °C 3: <NH4>2S; ethanol View Scheme
参考文献
Zhurnal Prikladnoi Khimii (Sankt-Peterburg, Russian Federation), , vol. 9, p. 304,314
Chem. Zentralbl., , vol. 107, # II p. 1543
参考文献
DE492250 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 16, p. 2682
参考文献
Journal of the American Chemical Society, , vol. 70, p. 44,48
Arhiv za Kemiju, , vol. 19, p. 38,41
Chem.Abstr., , p. 7724
参考文献
Elderfield et al.
Journal of the American Chemical Society, 1946 , vol. 68, p. 1524,1526
反应条件
1: in hexan-1-ol T=145°C; 21 h; 2: With sodium hydroxide in water; hexan-1-ol T=50 - 60°C;
参考文献
Wyeth
Patent: EP1147083 B1, 2004 ;
Location in patent: Page 41 ;
EP 1147083 B1
反应条件
1: 6-Methoxy-quinolin-8-ylamine; N-(2,2'-bischloro)diethyl amine in hexan-1-ol T=145°C; 21 h; 2: sodium hydroxide in water; hexan-1-ol T=50 - 60°C; Product distribution / selectivity;
参考文献
Wyeth
Patent: US2007/299083 A1, 2007 ;
Location in patent: Page/Page column 8-9 ;
US 20070299083 A1
参考文献
Drake et al.
Journal of the American Chemical Society, 1946 , vol. 68, p. 1542
参考文献
Armer, Richard E.; Barlow, Jacqueline S.; Chopra, Narinder; Dutton, Christopher J.; Greenway, David H.J.; Greenwood, Sean D.W.; Lad, Nita; Shaw, Jonothan; Thompson, Adrian P.; Thong, Kam-Wah; Tommasini, Ivan
Bioorganic and Medicinal Chemistry Letters, 1999 , vol. 9, # 16 p. 2425 - 2430
