(alphaS)-rel-alpha-[(1R)-1-(甲基氨基)乙基]-苯甲醇合成路线 （共 56 条）
反应条件
1: 84 percent / NaOH; Na2CO3 / dimethylformamide / 1.25 h / 25 °C 2: aluminum-copper alloy; aq. KOH / methanol / 24 h / 25 °C View Scheme
参考文献
Organic Preparations and Procedures International, , vol. 23, # 2 p. 139 - 146
反应条件
1: anisole; TFA / CH2Cl2 / 0.75 h 2: 0.098 g / Zn(BH4)2 / diethyl ether / 1 h / -78 °C View Scheme
参考文献
Canadian Journal of Chemistry, , vol. 82, # 2 p. 87 - 101
反应条件
1: 92 percent / N-methylmorpholine-N-oxide; 4 Angstroem molecular sieves; tetrapropylammonium perruthenate / CH2Cl2 / 1 h 2: anisole; TFA / CH2Cl2 / 0.75 h 3: 0.098 g / Zn(BH4)2 / diethyl ether / 1 h / -78 °C View Scheme
参考文献
Canadian Journal of Chemistry, , vol. 82, # 2 p. 87 - 101
反应条件
1: ethanol 2: palladium; aqueous hydrochloric acid / Hydrogenation View Scheme
参考文献
DE524717 , ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 17, p. 2515
反应条件
hydrogenchloride; palladium Hydrogenation;
参考文献
DE524717 , ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 17, p. 2515
反应条件
water; potassium hydroxide in ethanol 2 h; Reflux;
参考文献
Synthetic Communications, , vol. 40, # 10 p. 1461 - 1476
参考文献
DE673486 , ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 25, p. 339
反应条件
palladium Hydrogenation;
参考文献
DE472466 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 16, p. 2835
参考文献
Yakugaku Zasshi, , vol. 70, p. 212,215
Chem.Abstr., , p. 7273
反应条件
sodium amide; decalin
