氢氯吡格雷合成路线

90055-48-4氢氯吡格雷

113665-84-2氯吡格雷

参考文献

KANDULA, mahesh
Patent: WO2013/24376 A1, 2013 ;
Location in patent: Paragraph 00172; 00173 ;

90055-48-4氢氯吡格雷

135046-48-9硫酸氢氯吡格雷

参考文献

RICHTER GEDEON NYRT.
Patent: WO2009/77797 A1, 2009 ;
Location in patent: Page/Page column 13 ;

90055-48-4氢氯吡格雷

120202-66-6硫酸氯吡格雷

参考文献

DONG WHA PHARM. CO., LTD.; OH, Yoon Seok; SHIN, Dong Hyuk; JUNG, Jin Yong
Patent: WO2011/83955 A2, 2011 ;

90055-55-3+

77-78-1硫酸二甲酯

90055-48-4氢氯吡格雷

参考文献

KANDULA, Mahesh
Patent: WO2013/168022 A1, 2013 ;
Location in patent: Paragraph 00100; 00101 ;

135046-48-9硫酸氢氯吡格雷

90055-48-4氢氯吡格雷

参考文献

Craighead, Mark; Palin, Ronald; Murray, Neil; Lindsay, Derek
Patent: US2013/225594 A1, 2013 ;
Location in patent: Paragraph 0291; 0292 ;

120202-69-9氯吡格雷杂质C

90055-48-4氢氯吡格雷

参考文献

RICHTER GEDEON NYRT.
Patent: WO2009/77797 A1, 2009 ;
Location in patent: Page/Page column 12 ;

444728-11-4外消旋-2-(2-氯苯基)-(6,7-二氢-4H-噻吩并[3,2-c]吡啶-5-基)乙腈+

77-78-1硫酸二甲酯

90055-48-4氢氯吡格雷

参考文献

ZHEJIANG HUAHAI PHARMACEUTICAL CO., LTD.; CHENGDU ORGANIC CHEMICLAS CO., LTD CHINESE ACADEMY OF SCIENCES
Patent: US2008/249311 A1, 2008 ;
Location in patent: Page/Page column 11 ;

90055-47-32,2’-二氯苯乙酸甲酯+

28783-41-74,5,6,7-四氢噻吩并[3,2-c]吡啶盐酸盐

90055-48-4氢氯吡格雷

参考文献

Kalinski, Cedric; Lemoine, Hugues; Schmidt, Juergen; Burdack, Christoph; Kolb, Juergen; Umkehrer, Michael; Ross, Guenther
Synthesis, 2008 , # 24 art. no. T05808SS, p. 4007 - 4011

929200-19-1+

77-78-1硫酸二甲酯

90055-48-4氢氯吡格雷

参考文献

ZHEJIANG HUAHAI PHARMACEUTICAL CO., LTD.; CHENGDU ORGANIC CHEMICLAS CO., LTD CHINESE ACADEMY OF SCIENCES
Patent: US2008/249311 A1, 2008 ;
Location in patent: Page/Page column 12 ;

28783-42-8+

85259-19-4

90055-48-4氢氯吡格雷

参考文献

IND-SWIFT LABORATORIES LIMITED
Patent: WO2007/125544 A2, 2007 ;
Location in patent: Page/Page column 14-15 ;