N-[4,7-二氢-7-(甲氧基甲基)-3-甲基-4-氧代-3H-吡咯并[2,3-d]嘧啶-2-基]-乙酰胺合成路线 （共 3 条）
反应条件
sodium hydroxide
T=120°C; 2 h;
参考文献
Seela; Bussmann; Gotze; Rosemeyer
Journal of Medicinal Chemistry, 1984 , vol. 27, # 8 p. 981 - 985
反应条件
1: 60 percent / 50percent aq. NaOH, benzyltriethylammonium chloride / CH2Cl2; 1,2-dimethoxy-ethane / 1 h
2: 80 percent / NaOH / 2 h / 120 °C
View Scheme
参考文献
Seela; Bussmann; Gotze; Rosemeyer
Journal of Medicinal Chemistry, 1984 , vol. 27, # 8 p. 981 - 985
反应条件
1: BCl3 / CH2Cl2 / 17 h / -20 °C
2: conc. aq. ammonia / methanol / 17 h / Ambient temperature
View Scheme
参考文献
Seela; Bussmann; Gotze; Rosemeyer
Journal of Medicinal Chemistry, 1984 , vol. 27, # 8 p. 981 - 985
