4-氯-7-(甲氧基甲基)-7H-吡咯并[2,3-d]嘧啶-2-胺合成路线 (共 2 条)
反应条件
sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride in ethylene glycol dimethyl ether; dichloromethane
0.25 h;
参考文献
Seela; Bussmann; Gotze; Rosemeyer
Journal of Medicinal Chemistry, 1984 , vol. 27, # 8 p. 981 - 985
反应条件
1: 1 M NaOMe / methanol / 24 h / Heating
2: 1 M aq. NaOH / 4.5 h / Heating
View Scheme
参考文献
Seela; Bussmann; Gotze; Rosemeyer
Journal of Medicinal Chemistry, 1984 , vol. 27, # 8 p. 981 - 985