dicyclohexyl(2′,6′-dimethoxybiphenyl-2-yl)phosphine; potassium phosphate; palladium diacetate in tetrahydrofuran 16 h; Inert atmosphereReflux;

1: cyclopropyl-magnesium bromide With zinc(II) chloride in tetrahydrofuran T=20°C; 0.5 h; 2: 5-bromopyridine-3-carbonitrile With 1,1'-bis-(diphenylphosphino)ferrocene; tris-(dibenzylideneacetone)dipalladium(0) in tetrahydrofuran T=85°C; 12.0833 h;

hydrogen; nickel in methanol 2.66667 h;