反应条件
1: 97 percent / PBr3, pyridine / petroleum ether; diethyl ether / 1 h / -15 °C
2: 1.) 1 N KOH, 2.) KI / 2.) HMPT, 45 deg C, 16 h
View Scheme
参考文献
Schaffner-Sabba, Karl; Schmidt-Ruppin, Karl H.; Wehrli, Walter; Schuerch, ALfred R.; Wasley, Jan W. F.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 8 p. 990 - 994
