N,N-二甲基-3-(三氟甲基)苯酰胺合成路线 （共 6 条）
反应条件
2,4,6-trimethyl-pyridine; copper diacetate in N,N-dimethyl acetamide
T=25°C; P=760.051 Torr; 16 h; Inert atmosphere;
参考文献
Xu, Jun; Luo, Dong-Fen; Xiao, Bin; Liu, Zhao-Jing; Gong, Tian-Jun; Fu, Yao; Liu, Lei
Chemical Communications, 2011 , vol. 47, # 14 p. 4300 - 4302
反应条件
1H-imidazole; bis-triphenylphosphine-palladium(II) chloride; triphenylphosphine
T=120°C; P=3750.38 Torr; 18 h;
参考文献
Schnyder; Beller; Mehltretter; Nsenda; Studer; Indolese
Journal of Organic Chemistry, 2001 , vol. 66, # 12 p. 4311 - 4315
反应条件
copper(I) oxide; 1,10-phenanthroline; oxygen; toluene-4-sulfonic acid
T=140°C; P=760.051 Torr; 24 h; Sealed tube;
参考文献
Hu, Chenxu; Yan, Xufei; Zhou, Xiangge; Li, Zhengkai
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 47 p. 8179 - 8182
反应条件
tert.-butylhydroperoxide; CuO in water
T=85°C; 15 h;
参考文献
Priyadarshini; Amal Joseph; Lakshmi Kantam
RSC Advances, 2013 , vol. 3, # 40 p. 18283 - 18287
反应条件
sodium hydroxide in water; toluene
2 h;
参考文献
NEUROGEN CORPORATION
Patent: WO2005/7648 A2, 2005 ;
Location in patent: Page 63 ;
WO 2005/007648 A2
反应条件
1H-imidazole; bis-triphenylphosphine-palladium(II) chloride
T=120°C; P=3750.38 Torr; 18 h;
参考文献
Schnyder; Beller; Mehltretter; Nsenda; Studer; Indolese
Journal of Organic Chemistry, 2001 , vol. 66, # 12 p. 4311 - 4315
