(R)-2-羟基-3-甲基丁酸甲酯合成路线 （共 15 条）
反应条件
1: 65 percent / Et3N, DMAP / CH2Cl2 / 6 h / Ambient temperature
2: 75 percent / HCl / tetrahydrofuran; H2O / 3 h / Ambient temperature
3: KBH4 / methanol / 10 h / 0 °C
4: 58 percent / H2SO4 / H2O / 0.5 h / 90 °C
5: 75 percent
View Scheme
参考文献
Pansare, Sunil V.; Ravi, R. Gnana
Tetrahedron, 1998 , vol. 54, # 48 p. 14549 - 14564
反应条件
1: KBH4 / methanol / 10 h / 0 °C
2: 58 percent / H2SO4 / H2O / 0.5 h / 90 °C
3: 75 percent
View Scheme
参考文献
Pansare, Sunil V.; Ravi, R. Gnana
Tetrahedron, 1998 , vol. 54, # 48 p. 14549 - 14564
反应条件
1: 58 percent / H2SO4 / H2O / 0.5 h / 90 °C
2: 75 percent
View Scheme
参考文献
Pansare, Sunil V.; Ravi, R. Gnana
Tetrahedron, 1998 , vol. 54, # 48 p. 14549 - 14564
参考文献
Evans, D. A.; Morissey, M. M.; Dorow, R. L.
Journal of the American Chemical Society, 1985 , vol. 107, # 14 p. 4346 - 4348
参考文献
Nakazaki,M.; Arakawa,H.
Bulletin of the Chemical Society of Japan, 1961 , vol. 34, p. 1246 - 1249
