反应条件
1: LiCl, Me2SO, H2O / 2 h / Heating
2: H2SO4 / Ambient temperature
3: 69.2 percent / AlCl3 / 1,2-dichloro-ethane / 3.75 h / 5 - 20 °C
4: 20 percent / NH2OH*HCl, pyridine / 4 h / Heating
5: 58 percent / 1 h / 90 °C
6: NaH / dimethylformamide / 4 h / Ambient temperature
7: 92 percent / aq. KOH / methanol / 1 h
View Scheme
参考文献
Plattner; Fung; Parks; et al.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 8 p. 1016 - 1026
