1: anhydrous 1-octyne With n-butyllithium in tetrahydrofuran; hexane T=-78°C; Metallation; 0.5 h; 2: trans-1-chloro-2-iodoethylene With zinc dibromide; tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran; hexane T=0 - 25°C; Substitution; 1 h; Further stages.;

piperidine; copper(l) iodide; tetrakis(triphenylphosphine) palladium(0) in diethyl ether T=20°C; 2 h;

copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); N-butylamine in benzene T=23°C; 5 h; Inert atmosphere;

ammonia; sodium amide in diethyl ether 1 h;