2-氨基-6-甲基苯-1-磺酰胺合成路线 (共 4 条)
反应条件
1: With AlCl3, aluminium chloride in 1-nitroethane
T=-55 - 100°C;
2: With hydrogenchloride; water in 1,4-dioxane
T=120°C; 18 h;
参考文献
NOVARTIS AG; NOVARTIS PHARMA GMBH
Patent: WO2005/26130 A1, 2005 ;
Location in patent: Page/Page column 9-10 ;
WO 2005/026130 A1
参考文献
TEIJIN LIMITED
Patent: EP1505067 A1, 2005 ;
Location in patent: Page/Page column 380 ;
EP 1505067 A1
反应条件
nickel; ethyl acetate
Hydrogenation;
参考文献
Szabo
Bulletin de la Societe Chimique de France, 1953 , p. 771,773
反应条件
1: NH3
2: Raney nickel; ethyl acetate / Hydrogenation
View Scheme
参考文献
Szabo
Bulletin de la Societe Chimique de France, 1953 , p. 771,773