5-乙基-1-甲基-1H-四唑合成路线 (共 4 条)
反应条件
potassium carbonate in acetonitrile
18 h; Ambient temperature;
参考文献
Thomas, Edward W.; Cudahy, Michele M.
Journal of Organic Chemistry, 1993 , vol. 58, # 6 p. 1623 - 1627
反应条件
sodium azide in acetonitrile
3 h;
参考文献
Quast, Helmut; Bieber, Lothar; Meichsner, Georg
Liebigs Annalen der Chemie, 1987 , p. 469 - 476
反应条件
n-butyllithium
1.) THF, hexane, -78 deg C, 30 min, 2.) -78 deg C, 30 min; Yield given. Multistep reaction;
参考文献
Sit; Parker; Motoc; Han; Balasubramanian; Catt; Brown; Harte; Thompson; Wright
Journal of Medicinal Chemistry, 1990 , vol. 33, # 11 p. 2982 - 2999
反应条件
tin(ll) chloride; trimethylsilylacetylene
T=55°C; 20 h; Yield given. Yields of byproduct given;
参考文献
Nishiyama, Kozaburo; Watanabe, Akio
Chemistry Letters, 1984 , p. 455 - 458