5-(4,4,5,5-四甲基-1,3,2-二氧硼烷)-1-[[2-(三甲基甲硅烷基)乙氧基]甲基]-1H-吡唑合成路线 （共 2 条）
反应条件
1: 1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrazole With n-butyllithium in tetrahydrofuran
T=-70°C;
2: With tri-isopropoxy-borane in tetrahydrofuran
T=-70°C;
3: 2,3-dimethylbutane-2,3-diol With acetic acid in tetrahydrofuran
T=-70°C;
参考文献
Gerard, Anne-Laure; Bouillon, Alexandre; Mahatsekake, Clement; Collot, Valerie; Rault, Sylvain
Tetrahedron Letters, 2006 , vol. 47, # 27 p. 4665 - 4669
反应条件
1.1: 98 percent / sodium hydride / tetrahydrofuran / 20 °C
2.1: n-BuLi / tetrahydrofuran / -70 °C
2.2: triisopropylborate / tetrahydrofuran / -70 °C
2.3: 75 percent / AcOH / tetrahydrofuran / -70 °C
View Scheme
参考文献
Gerard, Anne-Laure; Bouillon, Alexandre; Mahatsekake, Clement; Collot, Valerie; Rault, Sylvain
Tetrahedron Letters, 2006 , vol. 47, # 27 p. 4665 - 4669
