2-氧代-1,2,3,4-四氢喹啉-7-甲腈合成路线 （共 3 条）
反应条件
tetrakis(triphenylphosphine) palladium(0) in N,N-dimethyl-formamide
T=80°C; 12.5 h;
参考文献
Alantos Pharmaceuticals, Inc.,
Patent: US2006/173183 A1, 2006 ;
Location in patent: Page/Page column 103-104 ;
反应条件
N,N,N',N,-tetramethylethylenediamine; 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene; tris-(dibenzylideneacetone)dipalladium(0) in N,N-dimethyl-formamide
T=180°C; 0.0833333 h; Microwave irradiation;
参考文献
TAISHO PHARMACEUTICAL CO., LTD.; KANUMA, Kosuke; MIYAKOSHI, Naoki; KAWAMURA, Madoka; SHIBATA, Tsuyoshi
Patent: WO2010/38901 A1, 2010 ;
Location in patent: Page/Page column 44-45 ;
WO 2010/038901 A1
反应条件
tetrakis(triphenylphosphine) palladium(0) in N,N-dimethyl-formamide
T=0 - 100°C;
参考文献
TAISHO PHARMACEUTICAL CO., LTD.; KANUMA, Kosuke; MIYAKOSHI, Naoki; KAWAMURA, Madoka; SHIBATA, Tsuyoshi
Patent: WO2010/38901 A1, 2010 ;
Location in patent: Page/Page column 75 ;
WO 2010/038901 A1
