7-氯-1-苯并噻吩-2-羧酸合成路线 （共 4 条）
反应条件
sodium hydroxide in ethanol; water
参考文献
Rahman, Loay K. A.; Scrowston, Richard M.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , # 3 p. 385 - 390
反应条件
1: 90 percent / NaOH / ethanol; H2O 2: Cu-quinoline View Scheme
参考文献
Rahman, Loay K. A.; Scrowston, Richard M.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , # 3 p. 385 - 390
反应条件
sodium carbonate in N,N,N',N',N'',N''-hexamethylphosphoric triamide
T=80°C; 24 h;
参考文献
Rahman, Loay K. A.; Scrowston, Richard M.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , # 3 p. 385 - 390
反应条件
1: 1.) NaNO2, hydrochloric acid, 2.) hydrated CuSO4, anhyd. NaSO3, NaOAc. 3.) hydrochloric acid
2: 85 percent / Na2CO3 / hexamethylphosphoric acid triamide / 24 h / 80 °C
View Scheme
参考文献
Rahman, Loay K. A.; Scrowston, Richard M.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , # 3 p. 385 - 390
